Antonine Severin Tibesar (1909–1992)

Filiae Augustorum: The Ties That Bind in the Antonine Age

Mechanism of interaction of Dictyostelium severin with actin filaments

Severin, a 40,000-dalton protein from Dictyostelium that disassembles actin filaments in a Ca2+ -dependent manner, was purified 500-fold to greater than 99% homogeneity by modifications of the procedure reported by Brown, Yamamoto, and Spudich (1982. J. Cell Biol. 93:205-210). Severin has a Stokes radius of 29 A and consists of a single polypeptide chain. It contains a single methionyl and five...

A mammalian severin replaces gelsolin in transformed epithelial cells.

A persisting paradox in cytoskeletal regulation of cell motility is the loss of the actin filament fragmenting protein, gelsolin, in transformed epithelial cells that have gained the ability to migrate. Either actin filament severing does not occur during motility of carcinoma cells or a novel fragmentation protein is expressed during transformation. Using an antibody specific for severin, the ...

Mechanism of Interaction Actin Filaments of Dictyostelium Severin with

Severin, a 40,000-dalton protein from Dictyostelium that disassembles actin filaments in a Ca2÷-dependent manner, was purified 500-fold to >99% homogeneity by modifications of the procedure reported by Brown, Yamamoto, and Spudich (1982. J. Cell Biol. 93:205210). Severin has a Stokes radius of 29/k and consists of a single polypeptide chain. !t contains a single methionyl and five cysteinyl res...

Princeton/Stanford Working Papers in Classics Roman wellbeing and the economic consequences of the ‘Antonine Plague’

This paper responds to recent scholarship by Willem Jongman and Geoffrey Kron that has tried to make a case for elevated levels of prosperity and physical wellbeing in the first two centuries of the Roman imperial monarchy. The relevance of various putative indicators is critiqued. Demographic data as well as anthropometric evidence consistently point to high levels of morbidity and mortality a...